| 1792 | CSMS Charter and First Meeting: Middletown, CT |
| 1793 | Physician Licensure Begun |
| 1812 | Medical Institution of Yale College (Yale University School of Medicine) |
| 1822 | Connecticut Retreat (Institute of Living) |
| 1826 | First General Hospital of Connecticut (Yale-New Haven Hospital) |
| 1841 | State Registry of Deaths and Their Causes |
| 1847 | National Medical Convention Led by Dr. Jonathan Knight of CSMS Founds the AMA |
| 1867 | Connecticut Valley Hospital (Middletown) |
| 1878 | Connecticut State Board of Health |
| 1892 | CSMS Centennial Celebration, New Haven |
| 1893 | Connecticut Medical Practice Act |
| 1935 | Connecticut Tumor Registry (World’s 1st Cancer Registry) |
| 1936 | Connecticut Medicine (Journal of the CSMS) |
| 1942 | CSMS Sesquicentennial Publication: The Heritage of Connecticut Medicine |
| 1947 | Connecticut Medical Service (CMS-Blue Shield) |
| 1949 | CSMS Headquarters Building (160 Saint Ronan Street, New Haven) |
| 1973 | CSMS CME Accreditation of Hospitals |
| 1974 | Connecticut SportsMed Newsletter |
| 1983 | Connecticut Peer Review Organization (CPRO, now Qualidigm) |
| 1984 | Connecticut Medical Insurance Co. (CMIC) |
| 1985 | CSMS/HCMA Medicare Courtesy Card Program (Now ConnPACE) |
| 1986 | CSMS-IPA/M.D. Health Plan |
| 1988 | CSMS Charitable Trust |
| 1988 | First CSMS Countersuit Pays $99,000 to CSMS Internist |
| 1990 | First Pictorial Directory of CSMS Physicians |
| 1991 | CSMS Health Awareness Campaign |
| 1992 | CSMS Bicentennial Benefit |
| 1993 | CSMS Workers’ Compensation Reform |
| 1994 | CSMS Headquarters Building Renovation |
| 1995 | CSMS Physicians’ Health and Education Fund |
| 1997 | The M.D. Makes the Difference! CSMS PR Campaign |
| 1999 | Aetna is Playing Doctor with Our Patients! CSMS Ad Campaign |
| 2001 | CSMS Class Action Lawsuits begin against 7 HMOs |
| 2002 | CSMS HIPAA Compliance Packets for Physicians |
| 2003 | 1,800 Doctors march on the Capitol in CSMS “White Coat Rally” |
| 2004 | Historic Aetna and Cigna Settlements of National Class Action covering 700,000 MDs |
| 2005 | Four More Settlements Achieved: HealthNet, prudential, Anthem/Wellpoint |
| 2006 | Matthew C. Katz succeeds Timothy B. Norbeck as CEO of CSMS |
| 2007 | P.A. 07-103 Establishes HAVEN, a Confidential Assistance Program for Health Care Professionals |
| 2008 | CSMS Publishes the Connecticut Physician Workforce Survey |
| 2009 | CSMS Received $400,000 healthcare Disparities Grant from Connecticut Health Foundation |
| 2010 | CSMS DVD: Care in Context: The Physician’s Role in Reducing Health Disparities |